Iimveliso
Lifecosm Leishmania Ab Test Kit
LSH Ab Test Kit
| Leishmania Ab Test Kit | |
| Inombolo yekhathalogu | I-RC-CF24 |
| Isishwankathelo | Ukufunyanwa kwee-antibodies ezithile zeLeishmaniakwimizuzu eli-10 |
| Umgaqo | Inyathelo elinye lovavanyo lwe-immunochromatographic |
| Iinjongo zokuFumana | L. chagasi, L. infantum, kunye ne-L. donovani antiboies |
| Isampulu | Igazi leCanine elipheleleyo, i-serum okanye iplasma |
| Ixesha lokufunda | 5 ~ 10 imizuzu |
| Uvakalelo | 98.9 % vs. IFA |
| Ukuchaza ngokuthe ngqo | 100.0 % vs. IFA |
| Umda wokuFumana | IFA Titer 1/32 |
| Ubungakanani | Ibhokisi ye-1 (ikhithi) = izixhobo ezili-10 (Ukupakishwa komntu ngamnye) |
| Imixholo | Ikhithi yovavanyo, ibhotile yeBuffer, kunye needropha eziLahlwayo |
| Ugcino | Ubushushu beGumbi (ku-2 ~ 30℃) |
| Ukuphelelwa lixesha | Iinyanga ezingama-24 emva kokuveliswa |
| Isilumkiso | Sebenzisa phakathi kwemizuzu eli-10 emva kokuvula Sebenzisa isixa esifanelekileyo sesampulu (0.01 ml yedropha) Sebenzisa emva kwemizuzu eyi-15 ~ 30 e-RT ukuba zigcinwe phantsi kweemeko ezibandayo Qwalasela iziphumo zovavanyo njengezingasebenziyo emva kwemizuzu eli-10 |
Ulwazi
I-Leishmaniasis sisifo esiyingozi kakhulu kwaye siyingozi ebantwini, iimazi kunye neekati.I-arhente ye-leishmaniasis yi-protozoan parasite kwaye iyinxalenye ye-leishmania donovani complex.Esi sifunxi-gazi sisasazwa kakhulu kumazwe apholileyo nasezantsi kweYurophu, eAfrika, eAsia, eMzantsi Melika nakuMbindi Merika.I-Leishmania donovani infantum (L. infantum) ijongene nesifo se-feline kunye ne-canine kuMzantsi Yurophu, e-Afrika, nase-Asia.I-Canine Leishmaniasis sisifo esiqhubekayo esiqhubekayo.Ayizizo zonke izinja ezihlakulela isifo seklinikhi emva kokugonywa kunye ne-parasites.Ukuphuhliswa kwesifo seklinikhi kuxhomekeke kuhlobo lwempendulo ye-immune eyenziwa yisilwanyana ngasinye
ngokuchasene nezifunxi-gazi.
Iimpawu
KwiCanine
Zombini ukubonakaliswa kwe-visceral kunye ne-cutaneous kunokufunyanwa ngaxeshanye ezinjeni;ngokungafaniyo nabantu, ii-syndromes ezihlukeneyo ze-cutaneous kunye ne-visceral azibonakali.Iimpawu zeklinikhi ziyaguquguquka kwaye zinokuxelisa olunye usulelo.Usulelo olungenazimpawu lunokwenzeka nalo.Iimpawu eziqhelekileyo ze-visceral zingabandakanya umkhuhlane (onokuthi ube ngamaxesha), i-anemia, i-lymphadenopathy, i-splenomegaly, i-lethargy, ukunciphisa ukunyamezela umthambo, ukunciphisa umzimba, kunye nokuncipha kokutya.Iimpawu ezincinci ze-visceral ziquka urhudo, ukuhlanza, i-melena, i-glomerulonephritis,
ukungasebenzi kwesibindi, i-epistaxis, i-polyuria-polydipsia, ukuthimla, ukuqhwalela (ngenxa yo
i-polyarthritis okanye i-myositis), i-ascites, kunye ne-colitis engapheliyo.
KwiFeline
Iikati azifane zosuleleke.Kwiikati ezininzi ezosulelekileyo, izilonda zikhawulelwe kwizilonda ze-cutaneous, zihlala zifumaneka emlonyeni, impumlo, iinkophe, okanye i-pinnae.Izilonda zeVisceral kunye neempawu zinqabile.
Umnqa wobomi
Umjikelo wobomi uqukunjelwa kwimikhosi emibini.Umnini wezilwanyana ezinomqolo kunye nomkhosi ongenamqolo (isanti).Imazi yempukane yesanti itya izilwanyana ezinomqolo kwaye iginya amastigotes.I-promastigotes ene-Flallelated ikhula kwinambuzane.Iipromastigotes zitofwa kwi-vertebrate host ngexesha lokutyisa i-sandfly.I-promastigotes ikhula ibe yi-amastigotes kwaye iphindaphindeka ngokuyinhloko kwi-macrophages.Ukuphindaphinda ngaphakathi macrophages ye
ulusu, ulusu kunye ne-viscera, ibangela i-cutaneous, i-mucosal kunye ne-visceral leishmaniasis ngokulandelelanayo.
Uxilongo
Ezinjeni, i-leishmaniasis idla ngokufunyaniswa ngokujongwa ngokuthe ngqo kwezifunxi-gazi, kusetyenziswa i-Giemsa okanye amabala akhawulezayo obunikazi, kwii-smears ezivela kwi-lymph node, i-spleen, okanye i-bone marrow aspirates, i-tissue biopsies, okanye i-scrapings yesikhumba kwizilonda.Izinto eziphilayo zinokufunyanwa kwizilonda zamehlo, ngakumbi kwiigranulomas.I-amastigotes ingqukuva ukuya kwi-oval parasites, kunye ne-nucleus engqukuva ye-basophilic kunye ne-kinetoplast encinci intonga.Zifumaneka kwii-macrophages okanye zikhululwe kwiiseli eziqhekekileyo.I-Immunohistochemistry kunye ne-polymerase chain reaction (PCR)
iindlela zobugcisa ziyasetyenziswa.
Uthintelo
Amachiza asetyenziswa ngokuqhelekileyo: I-Meglumine Antimoniate ehambelana ne-Allopurinol, i-Aminosidine, kwaye kutshanje, i-Amphotericin B. Zonke ezi ziyobisi zifuna i-regimen ye-dose eninzi, kwaye oku kuya kuxhomekeka kwimeko yesigulane kunye nentsebenziswano yomnini.Kucetyiswa ukuba unyango lwesondlo kufuneka lugcinwe kunye ne-allopurinol, kuba akunakwenzeka ukuqinisekisa ukuba izinja aziyi kuphinda zibuyele ukuba unyango luyekiwe.Ukusetyenziswa kweekhola eziqulethe amayeza okubulala izinambuzane, iishampoos okanye izitshizi ezisebenzayo ukukhusela izinja ekulunyweni kwesanti kufuneka zisetyenziswe ngokuqhubekayo kuzo zonke izigulana eziphantsi konyango.Ulawulo lwe-vector yenye yezona zinto zibalulekileyo zolawulo lwezifo.
I-sandfly isesichengeni sokubulala izinambuzane ezifanayo ne-malariya vector.
